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Comprehensive Meta Analysis V2 Crack

Comprehensive Meta Analysis V2: A Review of Features and Benefits

Meta-analysis is a statistical technique that combines the results of multiple studies to provide a summary estimate of the effect of an intervention, a risk factor, or a diagnostic test. Meta-analysis can help researchers to synthesize the existing evidence, identify sources of heterogeneity, and assess the quality and validity of the studies. However, conducting a meta-analysis can be challenging, especially for beginners or those who are not familiar with the methods and software.

One of the most popular and user-friendly software for meta-analysis is Comprehensive Meta Analysis (CMA), developed by Biostat Inc. CMA is a Windows-based program that allows users to perform various types of meta-analyses, such as fixed-effect, random-effects, meta-regression, subgroup analysis, publication bias, sensitivity analysis, and more. CMA also provides graphical tools to display the results, such as forest plots, funnel plots, Galbraith plots, L'Abbe plots, and more. CMA can handle different types of data, such as binary, continuous, correlation, or generic inverse variance. CMA can also import data from Excel, SPSS, Stata, or RevMan files.

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The latest version of CMA is version 4, which was released in 2020. However, some users may still prefer to use the previous version 2 (V2), which was released in 2005. V2 has some features and benefits that may not be available in V4 or other software. In this article, we will review some of the main features and benefits of CMA V2 and compare it with V4 and other software.

Features and Benefits of CMA V2

  • Simple and intuitive interface: CMA V2 has a simple and intuitive interface that guides users through the steps of conducting a meta-analysis. Users can easily enter or import data, choose the analysis options, and view the results in tables and graphs. Users can also access the help menu or the manual for more information and examples.

  • Flexible data entry: CMA V2 allows users to enter data in different formats, such as raw data (e.g., event rates, means and standard deviations), effect sizes (e.g., odds ratios, standardized mean differences), or generic inverse variance (e.g., log odds ratios and standard errors). Users can also enter data as subgroups or moderators to perform subgroup analysis or meta-regression. Users can also enter data as individual studies or as pooled estimates from other meta-analyses.

  • Comprehensive analysis options: CMA V2 offers a comprehensive range of analysis options for different types of meta-analyses. Users can choose between fixed-effect or random-effects models, depending on the assumption of heterogeneity. Users can also choose between different methods to calculate the effect sizes and their variances, such as Mantel-Haenszel, Peto, DerSimonian-Laird, Hedges-Olkin, Borenstein-Hedges-Olkin-Varkevisser-Rothstein (BHOR), or inverse variance. Users can also perform meta-regression to explore the effect of moderators on the effect sizes. Users can also perform subgroup analysis to compare the effect sizes across different subgroups. Users can also perform sensitivity analysis to assess the robustness of the results to different assumptions or methods. Users can also perform publication bias analysis to detect the presence and extent of publication bias using various methods, such as funnel plot, Egger's test, Begg's test, trim-and-fill method, Duval-Tweedie method, or fail-safe N.

  • Clear and informative output: CMA V2 provides clear and informative output for each analysis option. Users can view the results in tables and graphs that summarize the main findings and statistics. Users can also customize the output by changing the labels, colors, fonts, scales, or formats. Users can also export the output to other formats, such as Word, Excel, PowerPoint, PDF, JPEG, or TIFF.

  • Low cost and easy installation: CMA V2 has a low cost compared to other software for meta-analysis. The current price for a single-user license is $495, which includes free updates and technical support. The price for academic users is $395, and for students or residents is $195. Users can also download a free 10-day trial version from the website. CMA V2 is easy to install and does not require any additional software or components.

Comparison with CMA V4 and Other Software

Although CMA V2 has many features and benefits, it also has some limitations and drawbacks that may make users prefer to use the newer version 4 (V4) or other software. Here are some of the main differences and comparisons between CMA V2 and V4 or other software:

  • Updated methods and features: CMA V4 has some updated methods and features that are not available in V2, such as network meta-analysis, individual participant data meta-analysis, multivariate meta-analysis, meta-analysis of diagnostic test accuracy, prediction intervals, leave-one-out analysis, cumulative meta-analysis, subgroup differences test, mixed-effects meta-regression, Knapp-Hartung method, Hartung-Knapp-Sidik-Jonkman method, Paule-Mandel method, Sidik-Jonkman method, restricted maximum likelihood method, quality effects model, dose-response meta-analysis, and more. Users who need to perform these types of analyses may find V4 more suitable and comprehensive than V2.

  • Improved interface and output: CMA V4 has an improved interface and output that are more user-friendly and attractive than V2. For example, V4 has a ribbon menu that organizes the functions into tabs and groups. V4 also has a data grid that allows users to edit the data directly in the grid. V4 also has a results pane that displays the results in a tabbed format. V4 also has a graph pane that displays the graphs in a larger size and with more options. V4 also has a report pane that allows users to create a report with text, tables, and graphs. V4 also has a project pane that allows users to save and manage multiple projects in one file.

  • Compatibility and support: CMA V4 is more compatible and supported than V2. For example, V4 is compatible with Windows 10, while V2 may not work properly on newer versions of Windows. V4 is also compatible with Excel 2016 or later, while V2 may not import data from newer versions of Excel. V4 is also supported by Biostat Inc., while V2 is no longer supported or updated. Users who encounter problems or issues with V2 may not receive any help or solutions from the developers.

  • Other software: Besides CMA, there are other software for meta-analysis that users may consider using, such as RevMan, Stata, R, MetaXL, Meta-Essentials, or MetaWin. Each software has its own advantages and disadvantages in terms of features, functions, interface, output, cost, support, and learning curve. Users may need to compare and evaluate different software based on their needs and preferences.


CMA is a popular and user-friendly software for meta-analysis that offers a comprehensive range of analysis options and graphical tools. CMA V2 is an older version of the software that still has some features and benefits that may appeal to some users. However, CMA V4 is a newer version of the software that has some updated methods and features that are not available in V2. CMA V4 also has an improved interface and output that are more user-friendly and attractive than V2. CMA V4 is also more compatible and supported than V2. Users who need to perform meta-analysis may need to choose between CMA V2 and V4 or other software based on their needs and preferences.


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